You can modify profile settings in Cura. These settings are located on the right hand side of the screen. There are a multitude of settings that you can modify. To get to these setting you will have to move the slider to "Custom"
By default only some settings are shown. You can access all of the settings here by going to Preferences > Configure Cura > Settings > Click in the box labeled - Check All
Hovering your cursor over any setting will provide you with a brief explanation.
After you have made any changes to the slicing profile you will need to click the prepare button in the bottom right hand corner to re-slice the part. To save the change for later use you can click the active profile. Then choose from the 3 options shown in the third image.
A STAR in next to the name of a profile indicates that changes have been made to the active profile that have not been saved or discarded.
If at any time you would like to go back to default settings, access the profile manager and import a fresh profile (downloaded from the SeeMeCNC Github page)
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